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Aminoglycoside ribosome interactions reveal novel conformational states at ambient temperature

The bacterial 30S ribosomal subunit is a primary antibiotic target. Despite decades of discovery, the mechanisms by which antibiotic binding induces ribosomal dysfunction are not fully understood. Ambient temperature crystallographic techniques allow more biologically relevant investigation of how l...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: O’Sullivan, Mary E, Poitevin, Frédéric, Sierra, Raymond G, Gati, Cornelius, Dao, E Han, Rao, Yashas, Aksit, Fulya, Ciftci, Halilibrahim, Corsepius, Nicholas, Greenhouse, Robert, Hayes, Brandon, Hunter, Mark S, Liang, Mengling, McGurk, Alex, Mbgam, Paul, Obrinsky, Trevor, Pardo-Avila, Fátima, Seaberg, Matthew H, Cheng, Alan G, Ricci, Anthony J, DeMirci, Hasan
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182148/
https://ncbi.nlm.nih.gov/pubmed/30113694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky693
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