Aminoglycoside ribosome interactions reveal novel conformational states at ambient temperature

The bacterial 30S ribosomal subunit is a primary antibiotic target. Despite decades of discovery, the mechanisms by which antibiotic binding induces ribosomal dysfunction are not fully understood. Ambient temperature crystallographic techniques allow more biologically relevant investigation of how l...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: O’Sullivan, Mary E, Poitevin, Frédéric, Sierra, Raymond G, Gati, Cornelius, Dao, E Han, Rao, Yashas, Aksit, Fulya, Ciftci, Halilibrahim, Corsepius, Nicholas, Greenhouse, Robert, Hayes, Brandon, Hunter, Mark S, Liang, Mengling, McGurk, Alex, Mbgam, Paul, Obrinsky, Trevor, Pardo-Avila, Fátima, Seaberg, Matthew H, Cheng, Alan G, Ricci, Anthony J, DeMirci, Hasan
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Structural Biology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182148/
https://ncbi.nlm.nih.gov/pubmed/30113694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky693
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