A mating-type mutagenesis screen identifies a zinc-finger protein required for specific DNA excision events in Paramecium

In the ciliate Paramecium tetraurelia, functional genes are reconstituted during development of the somatic macronucleus through the precise excision of ∼45 000 single-copy Internal Eliminated Sequences (IESs), thought to be the degenerate remnants of ancient transposon insertions. Like introns, IES...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Bhullar, Simran, Denby Wilkes, Cyril, Arnaiz, Olivier, Nowacki, Mariusz, Sperling, Linda, Meyer, Eric
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Genome Integrity, Repair and Replication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182129/
https://ncbi.nlm.nih.gov/pubmed/30165457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky772
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