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Characterizing the protective effects of SHLP2, a mitochondrial-derived peptide, in macular degeneration

Mitochondrial-derived peptides (MDPs) are rapidly emerging therapeutic targets to combat development of neurodegenerative diseases. SHLP2 (small humanin-like peptide 2) is a newly discovered MDP that is coded from the MT-RNR2 (Mitochondrially encoded 16S rRNA) gene in mitochondrial DNA (mtDNA). In t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nashine, Sonali, Cohen, Pinchas, Nesburn, Anthony B., Kuppermann, Baruch D., Kenney, M. Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182005/
https://ncbi.nlm.nih.gov/pubmed/30310092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33290-5
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