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Single molecule localization microscopy coupled with touch preparation for the quantification of trastuzumab-bound HER2

All breast cancers are assessed for levels of human epidermal growth factor receptor 2 (HER2). Fluorescence in situ hybridization (FISH) and immunohistochemistry are currently used to determine if a patient is eligible for anti-HER2 therapy. Limitations of both tests include variability and relative...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tobin, Steven J., Wakefield, Devin L., Jones, Veronica, Liu, Xueli, Schmolze, Daniel, Jovanović-Talisman, Tijana
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181918/
https://ncbi.nlm.nih.gov/pubmed/30310083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33225-0
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