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Tau Activates Transposable Elements in Alzheimer’s Disease

Aging and neurodegenerative disease are characterized by genomic instability in neurons, including aberrant activation and mobilization of transposable elements (TEs). Integrating studies of human postmortem brain tissue and Drosophila melanogaster models, we investigate TE activation in association...

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Détails bibliographiques
Publié dans:Cell Rep
Auteurs principaux: Guo, Caiwei, Jeong, Hyun-Hwan, Hsieh, Yi-Chen, Klein, Hans-Ulrich, Bennett, David A., De Jager, Philip L., Liu, Zhandong, Shulman, Joshua M.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181645/
https://ncbi.nlm.nih.gov/pubmed/29874575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.05.004
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