Tau Activates Transposable Elements in Alzheimer’s Disease

Aging and neurodegenerative disease are characterized by genomic instability in neurons, including aberrant activation and mobilization of transposable elements (TEs). Integrating studies of human postmortem brain tissue and Drosophila melanogaster models, we investigate TE activation in association...

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Udgivet i:Cell Rep
Main Authors: Guo, Caiwei, Jeong, Hyun-Hwan, Hsieh, Yi-Chen, Klein, Hans-Ulrich, Bennett, David A., De Jager, Philip L., Liu, Zhandong, Shulman, Joshua M.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181645/
https://ncbi.nlm.nih.gov/pubmed/29874575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.05.004
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