The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space

Glioblastoma is characterized by widespread genetic and transcriptional heterogeneity, yet little is known about the role of the epigenome in glioblastoma disease progression. Here, we present genome-scale maps of DNA methylation in matched primary and recurring glioblastoma tumors, using data from...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Klughammer, Johanna, Kiesel, Barbara, Roetzer, Thomas, Fortelny, Nikolaus, Kuchler, Amelie, Nenning, Karl-Heinz, Furtner, Julia, Sheffield, Nathan C., Datlinger, Paul, Peter, Nadine, Nowosielski, Martha, Augustin, Marco, Mischkulnig, Mario, Ströbel, Thomas, Alpar, Donat, Ergüner, Bekir, Senekowitsch, Martin, Moser, Patrizia, Freyschlag, Christian F., Kerschbaumer, Johannes, Thomé, Claudius, Grams, Astrid E., Stockhammer, Günther, Kitzwoegerer, Melitta, Oberndorfer, Stefan, Marhold, Franz, Weis, Serge, Trenkler, Johannes, Buchroithner, Johanna, Pichler, Josef, Haybaeck, Johannes, Krassnig, Stefanie, Mahdy Ali, Kariem, von Campe, Gord, Payer, Franz, Sherif, Camillo, Preiser, Julius, Hauser, Thomas, Winkler, Peter A., Kleindienst, Waltraud, Würtz, Franz, Brandner-Kokalj, Tanisa, Stultschnig, Martin, Schweiger, Stefan, Dieckmann, Karin, Preusser, Matthias, Langs, Georg, Baumann, Bernhard, Knosp, Engelbert, Widhalm, Georg, Marosi, Christine, Hainfellner, Johannes A., Woehrer, Adelheid, Bock, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181207/
https://ncbi.nlm.nih.gov/pubmed/30150718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0156-x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados