CoQ(10) supplementation rescues nephrotic syndrome through normalization of H(2)S oxidation pathway

Nephrotic syndrome (NS), a frequent chronic kidney disease in children and young adults, is the most common phenotype associated with primary coenzyme Q(10) (CoQ(10)) deficiency and is very responsive to CoQ(10) supplementation, although the pathomechanism is not clear. Here, using a mouse model of...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Mol Basis Dis
Main Authors: Kleiner, Giulio, Barca, Emanuele, Ziosi, Marcello, Emmanuele, Valentina, Xu, Yimeng, Hidalgo-Gutierrez, Agustin, Qiao, Changhong, Tadesse, Saba, Area-Gomez, Estela, Lopez, Luis C., Quinzii, Catarina M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181133/
https://ncbi.nlm.nih.gov/pubmed/30251690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2018.09.002
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