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Comparing Multiple Machine Learning Algorithms and Metrics for Estrogen Receptor Binding Prediction

Many chemicals that disrupt endocrine function have been linked to a variety of adverse biological outcomes. However, screening for endocrine disruption using in vitro or in vivo approaches is costly and time-consuming. Computational methods, e.g. Quantitative Structure-Activity Relationship models,...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Pharm
Hauptverfasser: Russo, Daniel P., Zorn, Kimberley M., Clark, Alex M., Zhu, Hao, Ekins, Sean
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181119/
https://ncbi.nlm.nih.gov/pubmed/30114914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.8b00546
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