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Comparing and Validating Machine Learning Models for Mycobacterium tuberculosis Drug Discovery

Tuberculosis is a global health dilemma. In 2016, the WHO reported 10.4 million incidences and 1.7 million deaths. The need to develop new treatments for those infected with Mycobacterium tuberculosis (Mtb) has led to many large-scale phenotypic screens and many thousands of new active compounds ide...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Lane, Thomas, Russo, Daniel P., Zorn, Kimberley M., Clark, Alex M., Korotcov, Alexandru, Tkachenko, Valery, Reynolds, Robert C., Perryman, Alexander L., Freundlich, Joel S., Ekins, and Sean
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6167198/
https://ncbi.nlm.nih.gov/pubmed/29672063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.8b00083
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