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GLI2 promotes cell proliferation and migration through transcriptional activation of ARHGEF16 in human glioma cells
BACKGROUND: The Hedgehog (Hh) signaling pathway plays critical roles in modulating embryogenesis and maintaining tissue homeostasis, with glioma-associated oncogene (GLI) transcription factors being the main mediators. Aberrant activation of this pathway is associated with various human malignancies...
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| Publicado no: | J Exp Clin Cancer Res |
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| Principais autores: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6180656/ https://ncbi.nlm.nih.gov/pubmed/30305138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0917-x |
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