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Gain of function in Mycobacterium bovis BCG Moreau due to loss of a transcriptional repressor
The Bacille Calmette-Guérin (BCG) vaccine comprises a family of genetically different strains derived by the loss of genomic regions (RDs) and other mutations. In BCG Moreau, loss of RD16 inactivates rv3405c (*) , encoding a transcriptional repressor that negatively regulates the expression of Rv340...
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| Publicado no: | Mem Inst Oswaldo Cruz |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Instituto Oswaldo Cruz, Ministério da Saúde
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6180650/ https://ncbi.nlm.nih.gov/pubmed/30328891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/0074-02760180267 |
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