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Modulation of humoral immune response to oral BCG vaccination by Mycobacterium bovis BCG Moreau Rio de Janeiro (RDJ) in healthy adults

BACKGROUND: Oral administration of BCG was the route initially used by Calmette and Guérin, but was replaced by intradermal administration in virtually all countries after the Lubeck accident. However, Brazil continued to administer oral BCG Moreau RDJ, which was maintained until the mid-1970s when...

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Main Authors: Monteiro-Maia, Renata, Ortigão-de-Sampaio, Maria B, Pinho, Rosa T, Castello-Branco, Luiz RR
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569376/
https://ncbi.nlm.nih.gov/pubmed/16956404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-8518-4-4
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