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Combined study on clastogenic, aneugenic and apoptotic properties of doxorubicin in human cells in vitro
BACKGROUND: Doxorubicin is a widely used anticancer drug due to its broad spectrum of antitumor activity. Various mechanisms have been proposed for its cytostatic activity, including DNA intercalation, topoisomerase II inhibition, generation of free radicals and apoptosis. The present study aims to...
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| Publicado no: | J Biol Res (Thessalon) |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6180587/ https://ncbi.nlm.nih.gov/pubmed/30338246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40709-018-0089-z |
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