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Synthetic biology approaches and combinatorial biosynthesis towards heterologous lipopeptide production

Synthetic biology techniques coupled with heterologous secondary metabolite production offer opportunities for the discovery and optimisation of natural products. Here we developed a new assembly strategy based on type IIS endonucleases and elaborate synthetic DNA platforms, which could be used to s...

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Publicado en:Chem Sci
Main Authors: Yan, Fu, Burgard, Christian, Popoff, Alexander, Zaburannyi, Nestor, Zipf, Gregor, Maier, Josef, Bernauer, Hubert S., Wenzel, Silke C., Müller, Rolf
Formato: Artigo
Idioma:Inglês
Publicado: Royal Society of Chemistry 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180311/
https://ncbi.nlm.nih.gov/pubmed/30319751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc02046a
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