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Heterologous expression of the atypical tetracycline chelocardin reveals the full set of genes required for its biosynthesis
BACKGROUND: Chelocardin (CHD) exhibits a broad-spectrum antibiotic activity and showed promising results in a small phase II clinical study conducted on patients with urinary tract infections. Importantly, CHD was shown to be active also against tetracycline-resistant Gram-negative pathogens, which...
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| Publicado no: | Microb Cell Fact |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7749508/ https://ncbi.nlm.nih.gov/pubmed/33341113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-020-01495-x |
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