Glucocorticoids Induce Stress Oncoproteins Associated with Therapy-Resistance in African American and European American Prostate Cancer Cells

Glucocorticoid receptor (GR) is emerging as a key driver of prostate cancer (PCa) progression and therapy resistance in the absence of androgen receptor (AR) signaling. Acting as a bypass mechanism, GR activates AR-regulated genes, although GR-target genes contributing to PCa therapy resistance rema...

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Publicat a:Sci Rep
Autors principals: Woods-Burnham, Leanne, Cajigas-Du Ross, Christina K., Love, Arthur, Basu, Anamika, Sanchez-Hernandez, Evelyn S., Martinez, Shannalee R., Ortiz-Hernández, Greisha L., Stiel, Laura, Durán, Alfonso M., Wilson, Colwick, Montgomery, Susanne, Roy, Sourav, Casiano, Carlos A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180116/
https://ncbi.nlm.nih.gov/pubmed/30305646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33150-2
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