KIF6 gene as a pharmacogenetic marker for lipid-lowering effect in statin treatment

INTRODUCTION: The therapeutic response to statins has a high interindividual variability with respect to reductions in plasma LDL-cholesterol (c-LDL) and increases in HDL cholesterol (c-HDL). Many studies suggest that there is a relationship between the rs20455 KIF6 gene variant (c.2155T> C, Trp7...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Ruiz-Iruela, Cristina, Padró-Miquel, Ariadna, Pintó-Sala, Xavier, Baena-Díez, Neus, Caixàs-Pedragós, Assumpta, Güell-Miró, Roser, Navarro-Badal, Rosa, Jusmet-Miguel, Xavier, Calmarza, Pilar, Puzo-Foncilla, José Luis, Alía-Ramos, Pedro, Candás-Estébanez, Beatriz
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6179259/
https://ncbi.nlm.nih.gov/pubmed/30304062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205430
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