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APOE Variants E2, E3, and E4 Can Be Miscalled By Classical PCR‐RFLP When The Christchurch Variant Is Also Present

BACKGROUND: The APOE Christchurch (APOECh) is a rare variant (c.543C>A) in codon 154. It was first described in an E2 patient with type III dyslipidemia, and thus initially called E2Ch. Its prevalence and the lipid profile of carriers remain unclear. METHODS: E2, E3, and E4 screening for the APOE...

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Dades bibliogràfiques
Publicat a:J Clin Lab Anal
Autors principals: Candás‐Estébanez, Beatriz, Padró‐Miquel, Ariadna, Ruiz‐Iruela, Cristina, Corbella‐Inglés, Emili, Pintó‐Sala, Xavier, Alía‐Ramos, Pedro
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817017/
https://ncbi.nlm.nih.gov/pubmed/27566675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.22040
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