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Computational Modelling Reveals Signaling Lipids Modulate the Orientation of K-Ras4A at the Membrane Reflecting Protein Topology
The structural, dynamical and functional characterization of the small GTPase K-Ras has become a research area of intense focus due to its high occurrence in human cancers. Ras proteins are only fully functional when they interact with the plasma membrane. Here we present all atom molecular dynamics...
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| Publicado en: | Structure |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6178820/ https://ncbi.nlm.nih.gov/pubmed/28286004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.02.007 |
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