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Adenosine 2A Receptor Antagonists for the Treatment of Motor Symptoms in Parkinson's Disease

BACKGROUND: Treatment of motor fluctuations in Parkinson's disease (PD) remains an unmet challenge. Adenosine 2A (A(2A)) receptors are located along the indirect pathway and represent a potential target to enhance l‐3,4‐dihydroxyphenylalanine (l‐DOPA) antiparkinsonian action. METHODS: This arti...

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Detalhes bibliográficos
Publicado no:Mov Disord Clin Pract
Main Authors: Pourcher, Emmanuelle, Huot, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6178748/
https://ncbi.nlm.nih.gov/pubmed/30363540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mdc3.12187
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