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Dysarthria and Stutter as Presenting Symptoms of Late‐Onset Tay‐Sachs Disease in Three Siblings

Late‐onset Tay‐Sachs disease (LOTS) is a rare autosomal‐recessive genetic disorder caused by insufficient activity of the lysosomal enzyme, beta‐hexosaminidase A, resulting in intracellular accumulation of gangliosides in the central nervous system. Clinical manifestations can include unsteadiness i...

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Bibliografski detalji
Izdano u:Mov Disord Clin Pract
Glavni autori: Grim, Kristina K., Phillips, Gregory D., Renner, David R.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6178690/
https://ncbi.nlm.nih.gov/pubmed/30363497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mdc3.12194
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