Tracking Tumor Colonization in Xenograft Mouse Models Using Accelerator Mass Spectrometry

Here we introduce an Accelerator Mass Spectrometry (AMS)-based high precision method for quantifying the number of cancer cells that initiate metastatic tumors, in xenograft mice. Quantification of (14)C per cell prior to injection into animals, and quantification of (14)C in whole organs allows us...

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Publicado en:Sci Rep
Main Authors: Hum, Nicholas R., Martin, Kelly A., Malfatti, Michael A., Haack, Kurt, Buchholz, Bruce A., Loots, Gabriela G.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6178347/
https://ncbi.nlm.nih.gov/pubmed/30302019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33368-0
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