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Mutually orthogonal DNA replication systems in vivo
The yeast cytoplasmically-localized pGKL1/TP-DNAP1 plasmid/DNA polymerase pair forms an orthogonal DNA replication system whose mutation rate can be drastically increased without influencing genomic replication, thereby supporting in vivo continuous evolution. Here, we report that the pGKL2/TP-DNAP2...
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| 出版年: | ACS Synth Biol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6177532/ https://ncbi.nlm.nih.gov/pubmed/29969238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.8b00195 |
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