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Automated continuous evolution of proteins in vivo

We present automated continuous evolution (ACE), a platform for the hands-free directed evolution of biomolecules. ACE pairs OrthoRep, a genetic system for continuous targeted mutagenesis of user-selected genes in vivo, with eVOLVER, a scalable and automated continuous culture device for precise, mu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:ACS Synth Biol
Egile Nagusiak: Zhong, Ziwei, Wong, Brandon G., Ravikumar, Arjun, Arzumanyan, Garri A., Khalil, Ahmad S., Liu, Chang C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370864/
https://ncbi.nlm.nih.gov/pubmed/32374988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.0c00135
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