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Morphological changes, nitric oxide production, and phagocytosis are triggered in vitro in microglia by bloodstream forms of Trypanosoma brucei

The flagellated parasite Trypanosoma brucei is the causative agent of Human African Trypanosomiasis (HAT). By a mechanism not well understood yet, trypanosomes enter the central nervous system (CNS), invade the brain parenchyma, and cause a fatal encephalopathy if is not treated. Trypanosomes are fa...

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Publicado en:Sci Rep
Main Authors: Figarella, Katherine, Uzcategui, Nestor L., Mogk, Stefan, Wild, Katleen, Fallier-Becker, Petra, Neher, Jonas J., Duszenko, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177420/
https://ncbi.nlm.nih.gov/pubmed/30302029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33395-x
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