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Morphological changes, nitric oxide production, and phagocytosis are triggered in vitro in microglia by bloodstream forms of Trypanosoma brucei

The flagellated parasite Trypanosoma brucei is the causative agent of Human African Trypanosomiasis (HAT). By a mechanism not well understood yet, trypanosomes enter the central nervous system (CNS), invade the brain parenchyma, and cause a fatal encephalopathy if is not treated. Trypanosomes are fa...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Figarella, Katherine, Uzcategui, Nestor L., Mogk, Stefan, Wild, Katleen, Fallier-Becker, Petra, Neher, Jonas J., Duszenko, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177420/
https://ncbi.nlm.nih.gov/pubmed/30302029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33395-x
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