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A pharmacogenetics study of the human glucuronosyltransferase UGT1A4

UGT1A4 is primarily expressed in the liver and exhibits catalytic activities for various drugs. Amongst the few UGT1A4 polymorphisms evaluated, studies support the alteration of UGT1A4-mediated glucuronidation by a few variations including the Pro(24)Thr and Leu(48)Val variants (referred to as UGT1A...

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Detalhes bibliográficos
Publicado no:Pharmacogenet Genomics
Main Authors: Benoit-Biancamano, Marie-Odile, Adam, Jean-Philippe, Bernard, Olivier, Court, Michael H., Leblanc, Marie-Hélène, Caron, Patrick, Guillemette, Chantal
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177227/
https://ncbi.nlm.nih.gov/pubmed/19890225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e3283331637
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