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Effects of genetic deletion versus pharmacological blockade of the LPA(1) receptor on depression-like behaviour and related brain functional activity

Animal models of psychopathology are particularly useful for studying the neurobiology of depression and characterising the subtypes. Recently, our group was the first to identify a possible relationship between the LPA(1) receptor and a mixed anxiety-depression phenotype. Specifically, maLPA(1)-nul...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Moreno-Fernández, Román Darío, Nieto-Quero, Andrea, Gómez-Salas, Francisco Javier, Chun, Jerold, Estivill-Torrús, Guillermo, Rodríguez de Fonseca, Fernando, Santín, Luis Javier, Pérez-Martín, Margarita, Pedraza, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177006/
https://ncbi.nlm.nih.gov/pubmed/30061118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.035519
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