Aggravation of Chronic Stress Effects on Hippocampal Neurogenesis and Spatial Memory in LPA(1) Receptor Knockout Mice

BACKGROUND: The lysophosphatidic acid LPA(1) receptor regulates plasticity and neurogenesis in the adult hippocampus. Here, we studied whether absence of the LPA(1) receptor modulated the detrimental effects of chronic stress on hippocampal neurogenesis and spatial memory. METHODOLOGY/PRINCIPAL FIND...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Castilla-Ortega, Estela, Hoyo-Becerra, Carolina, Pedraza, Carmen, Chun, Jerold, Rodríguez De Fonseca, Fernando, Estivill-Torrús, Guillermo, Santín, Luis J.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183048/
https://ncbi.nlm.nih.gov/pubmed/21980482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025522
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires