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Aggravation of Chronic Stress Effects on Hippocampal Neurogenesis and Spatial Memory in LPA(1) Receptor Knockout Mice
BACKGROUND: The lysophosphatidic acid LPA(1) receptor regulates plasticity and neurogenesis in the adult hippocampus. Here, we studied whether absence of the LPA(1) receptor modulated the detrimental effects of chronic stress on hippocampal neurogenesis and spatial memory. METHODOLOGY/PRINCIPAL FIND...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3183048/ https://ncbi.nlm.nih.gov/pubmed/21980482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025522 |
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