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The small G protein Arl8 contributes to lysosomal function and long-range axonal transport in Drosophila
The small GTPase Arl8 has emerged as a major regulatory GTPase on lysosomes. Studies in mammalian cells have shown that it regulates both fusion with late endosomes and also lysosomal motility. In its active GTP-bound state, it recruits to lysosomes the HOPS (homotypic fusion and protein sorting) en...
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| Publicado no: | Biol Open |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6176938/ https://ncbi.nlm.nih.gov/pubmed/30115618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.035964 |
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