The Impact of NOD2 Variants on Fecal Microbiota in Crohn’s Disease and Controls Without Gastrointestinal Disease

BACKGROUND/AIMS: Current models of Crohn’s disease (CD) describe an inappropriate immune response to gut microbiota in genetically susceptible individuals. NOD2 variants are strongly associated with development of CD, and NOD2 is part of the innate immune response to bacteria. This study aimed to id...

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Dettagli Bibliografici
Pubblicato in:Inflamm Bowel Dis
Autori principali: Kennedy, Nicholas A, Lamb, Christopher A, Berry, Susan H, Walker, Alan W, Mansfield, John, Parkes, Miles, Simpkins, Rachel, Tremelling, Mark, Nutland, Sarah, Parkhill, Julian, Probert, Chris, Hold, Georgina L, Lees, Charlie W
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
Soggetti:
Original Research Articles–Basic Science
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176884/
https://ncbi.nlm.nih.gov/pubmed/29462388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ibd/izx061
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