The Impact of NOD2 Variants on Fecal Microbiota in Crohn’s Disease and Controls Without Gastrointestinal Disease

BACKGROUND/AIMS: Current models of Crohn’s disease (CD) describe an inappropriate immune response to gut microbiota in genetically susceptible individuals. NOD2 variants are strongly associated with development of CD, and NOD2 is part of the innate immune response to bacteria. This study aimed to id...

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Detalhes bibliográficos
Publicado no:Inflamm Bowel Dis
Main Authors: Kennedy, Nicholas A, Lamb, Christopher A, Berry, Susan H, Walker, Alan W, Mansfield, John, Parkes, Miles, Simpkins, Rachel, Tremelling, Mark, Nutland, Sarah, Parkhill, Julian, Probert, Chris, Hold, Georgina L, Lees, Charlie W
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Original Research Articles–Basic Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176884/
https://ncbi.nlm.nih.gov/pubmed/29462388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ibd/izx061
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