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Shaping the glioma immune microenvironment through tryptophan metabolism

The metabolism of the essential amino acid tryptophan is a key microenvironmental factor shaping the immunobiology of many tumor types. The current concept suggests that in the tumor microenvironment, tryptophan is metabolized by specialized dioxygenases, chiefly indoleamine-2,3-dioxygenase (IDO), w...

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Detalles Bibliográficos
Publicado en:CNS Oncol
Main Authors: Platten, Michael, Weller, Michael, Wick, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado: Future Medicine Ltd 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176840/
https://ncbi.nlm.nih.gov/pubmed/25054303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/cns.12.6
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