Frequent PTEN loss and Differential HER2/PI3K signaling pathway alterations in Salivary duct carcinoma: Implications for targeted therapy

BACKGROUND: Patients with advanced primary and recurrent salivary duct carcinoma (SDC), a rare and lethal malignancy, have limited therapeutic options. Novel small molecule agents aimed at targeting critical signaling associated with SDC tumorigenesis may lead to new therapeutic options in patients...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cancer
मुख्य लेखकों: Saintigny, Pierre, Mitani, Yoshitsugu, Pytynia, Kristen B, Ferrarotto, Renata, Roberts, Dianna B., Weber, Randal S., Kies, Merrill S., Maity, Sankar N., Lin, Sue-Hwa, El-Naggar, Adel K.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2018
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176717/
https://ncbi.nlm.nih.gov/pubmed/30289966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.31600
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