Frequent PTEN loss and Differential HER2/PI3K signaling pathway alterations in Salivary duct carcinoma: Implications for targeted therapy

BACKGROUND: Patients with advanced primary and recurrent salivary duct carcinoma (SDC), a rare and lethal malignancy, have limited therapeutic options. Novel small molecule agents aimed at targeting critical signaling associated with SDC tumorigenesis may lead to new therapeutic options in patients...

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Bibliografiske detaljer
Udgivet i:Cancer
Main Authors: Saintigny, Pierre, Mitani, Yoshitsugu, Pytynia, Kristen B, Ferrarotto, Renata, Roberts, Dianna B., Weber, Randal S., Kies, Merrill S., Maity, Sankar N., Lin, Sue-Hwa, El-Naggar, Adel K.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176717/
https://ncbi.nlm.nih.gov/pubmed/30289966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.31600
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