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Repurposing type III polyketide synthase as a malonyl-CoA biosensor for metabolic engineering in bacteria
Malonyl-CoA is an important central metabolite for the production of diverse valuable chemicals including natural products, but its intracellular availability is often limited due to the competition with essential cellular metabolism. Several malonyl-CoA biosensors have been developed for high-throu...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6176597/ https://ncbi.nlm.nih.gov/pubmed/30232266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808567115 |
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