A-kinase anchoring protein 12 is downregulated in human hepatocellular carcinoma and its deficiency in mice aggravates thioacetamide-induced liver injury

AKAP12 belongs to A-kinase anchoring protein (AKAP) family of scaffold proteins and is known as a tumor suppressor in several human cancer types. Its role as a tumor suppressor in hepatocellular carcinoma (HCC) was proposed due to its downregulation and epigenetic modification in human HCC; however,...

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Vydáno v:Oncol Lett
Hlavní autoři: Lee, Hye Shin, Choi, Jinhyeok, Son, Taekwon, Lee, Eun Ji, Kim, Jeong-Gyun, Ryu, Soo Hyung, Lee, Danbi, Jang, Myoung Kuk, Yu, Eunsil, Chung, Young-Hwa, Gelman, Irwin H., Kim, Kyu-Won
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2018
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176350/
https://ncbi.nlm.nih.gov/pubmed/30344741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.9396
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