Altered AKAP12 expression in portal fibroblasts and liver sinusoids mediates transition from hepatic fibrogenesis to fibrosis resolution

Liver fibrosis can be reversed by removing its causative injuries; however, the molecular mechanisms mediating the resolution of liver fibrogenesis are poorly understood. We investigate the role of a scaffold protein, A-Kinase Anchoring Protein 12 (AKAP12), during liver fibrosis onset, and resolutio...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Lee, Hye Shin, Choi, Jinhyeok, Son, Taekwon, Wee, Hee-Jun, Bae, Sung-Jin, Seo, Ji Hae, Park, Ji Hyun, Ryu, Soo Hyung, Lee, Danbi, Jang, Myoung Kuk, Yu, Eunsil, Chung, Young-Hwa, Kim, Kyu-Won
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938025/
https://ncbi.nlm.nih.gov/pubmed/29700280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0074-5
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