Plasma PIK3CA ctDNA specific mutation detected by next generation sequencing is associated with clinical outcome in advanced breast cancer

Through next generation sequencing, this study evaluated the circulating tumor DNA (ctDNA) of advanced breast cancer patients to prospectively explore the relationship between specific DNA mutations and prognosis as well as therapeutic decision making. The target region covered 1021 gene totally. Cl...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Li, Huiping, Xu, Yaping, Zhao, Fangyuan, Song, Guohong, Rugo, Hope S, Zhang, Yan, Yang, Ling, Liu, Xiaoran, Shao, Bin, Yang, Liang, Liu, Yaxin, Ran, Ran, Zhang, Ruyan, Guan, Yanfang, Chang, Lianpeng, Yi, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176180/
https://ncbi.nlm.nih.gov/pubmed/30323979
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