Detection of Rare Mutations in CtDNA Using Next Generation Sequencing

The analysis of circulating tumor DNA (ctDNA) using next-generation sequencing (NGS) has become a valuable tool for the development of clinical oncology. However, the application of this method is challenging due to its low sensitivity in analyzing the trace amount of ctDNA in the blood. Furthermore...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Lv, Xiaoxing, Zhao, Meiru, Yi, Yuting, Zhang, Lucheng, Guan, Yanfang, Liu, Tao, Yang, Ling, Chen, Rongrong, Ma, Jianhui, Yi, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2017
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614374/
https://ncbi.nlm.nih.gov/pubmed/28872127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/56342
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