Growth Hormone (GH) Deficient Mice With GHRH Gene Ablation Are Severely Deficient in Vaccine and Immune Responses Against Streptococcus pneumoniae

The precise impact of the somatotrope axis upon the immune system is still highly debated. We have previously shown that mice with generalized ablation of growth hormone (GH) releasing hormone (GHRH) gene (Ghrh(−/−)) have normal thymus and T-cell development, but present a marked spleen atrophy and...

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Bibliografiska uppgifter
I publikationen:Front Immunol
Huvudupphovsmän: Farhat, Khalil, Bodart, Gwennaëlle, Charlet-Renard, Chantal, Desmet, Christophe J., Moutschen, Michel, Beguin, Yves, Baron, Frédéric, Melin, Pierrette, Quatresooz, Pascale, Parent, Anne-Simone, Desmecht, Daniel, Sirard, Jean-Claude, Salvatori, Roberto, Martens, Henri, Geenen, Vincent G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2018
Ämnen:
Immunology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176084/
https://ncbi.nlm.nih.gov/pubmed/30333823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02175
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