Impact of Growth Hormone (GH) Deficiency and GH Replacement upon Thymus Function in Adult Patients

BACKGROUND: Despite age-related adipose involution, T cell generation in the thymus (thymopoiesis) is maintained beyond puberty in adults. In rodents, growth hormone (GH), insulin-like growth factor-1 (IGF-1), and GH secretagogues reverse age-related changes in thymus cytoarchitecture and increase t...

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Detalhes bibliográficos
Main Authors: Morrhaye, Gabriel, Kermani, Hamid, Legros, Jean-Jacques, Baron, Frederic, Beguin, Yves, Moutschen, Michel, Cheynier, Remi, Martens, Henri J., Geenen, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682582/
https://ncbi.nlm.nih.gov/pubmed/19479077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005668
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