TACI Isoforms Regulate Ligand Binding and Receptor Function

TACI signals activate B cell proliferation, isotype switch and antibody production in both normal immunity and autoimmune states. In contrast to murine TACI, the human TACI gene undergoes alternative splicing to produce short and long isoforms (TACI-S and TACI-L). In previous studies, we showed that...

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Detaylı Bibliyografya
Yayımlandı:Front Immunol
Asıl Yazarlar: Garcia-Carmona, Yolanda, Ting, Adrian T., Radigan, Lin, Athuluri Divakar, Sai Krishna, Chavez, Jose, Meffre, Eric, Cerutti, Andrea, Cunningham-Rundles, Charlotte
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2018
Konular:
Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176016/
https://ncbi.nlm.nih.gov/pubmed/30333819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02125
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