TACI Isoforms Regulate Ligand Binding and Receptor Function

TACI signals activate B cell proliferation, isotype switch and antibody production in both normal immunity and autoimmune states. In contrast to murine TACI, the human TACI gene undergoes alternative splicing to produce short and long isoforms (TACI-S and TACI-L). In previous studies, we showed that...

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Bibliografische gegevens
Gepubliceerd in:Front Immunol
Hoofdauteurs: Garcia-Carmona, Yolanda, Ting, Adrian T., Radigan, Lin, Athuluri Divakar, Sai Krishna, Chavez, Jose, Meffre, Eric, Cerutti, Andrea, Cunningham-Rundles, Charlotte
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2018
Onderwerpen:
Immunology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176016/
https://ncbi.nlm.nih.gov/pubmed/30333819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02125
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