Ultrasmall targeted nanoparticles with engineered antibody fragments for imaging detection of HER2-overexpressing breast cancer

Controlling the biodistribution of nanoparticles upon intravenous injection is the key to achieving target specificity. One of the impediments in nanoparticle-based tumor targeting is the inability to limit the trafficking of nanoparticles to liver and other organs leading to smaller accumulated amo...

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Vydáno v:Nat Commun
Hlavní autoři: Chen, Feng, Ma, Kai, Madajewski, Brian, Zhuang, Li, Zhang, Li, Rickert, Keith, Marelli, Marcello, Yoo, Barney, Turker, Melik Z., Overholtzer, Michael, Quinn, Thomas P., Gonen, Mithat, Zanzonico, Pat, Tuesca, Anthony, Bowen, Michael A., Norton, Larry, Subramony, J. Anand, Wiesner, Ulrich, Bradbury, Michelle S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175906/
https://ncbi.nlm.nih.gov/pubmed/30297810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06271-5
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