Notch1 regulates the initiation of metastasis and self-renewal of Group 3 medulloblastoma

Medulloblastoma is the most common malignant brain tumor of childhood. Group 3 medulloblastoma, the most aggressive molecular subtype, frequently disseminates through the leptomeningeal cerebral spinal fluid (CSF) spaces in the brain and spinal cord. The mechanism of dissemination through the CSF re...

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Udgivet i:Nat Commun
Main Authors: Kahn, Suzana A., Wang, Xin, Nitta, Ryan T., Gholamin, Sharareh, Theruvath, Johanna, Hutter, Gregor, Azad, Tej D., Wadi, Lina, Bolin, Sara, Ramaswamy, Vijay, Esparza, Rogelio, Liu, Kun-Wei, Edwards, Michael, Swartling, Fredrik J., Sahoo, Debashis, Li, Gordon, Wechsler-Reya, Robert J., Reimand, Jüri, Cho, Yoon-Jae, Taylor, Michael D., Weissman, Irving L., Mitra, Siddhartha S., Cheshier, Samuel H.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175869/
https://ncbi.nlm.nih.gov/pubmed/30297829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06564-9
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