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Comprehensive genomic profiling of metastatic tumors in a phase II biomarker study of everolimus in advanced renal cell carcinoma
PURPOSE: Genomic events leading to activation of mechanistic target of rapamycin (mTOR) are common in renal cell carcinoma (RCC). Everolimus is an allosteric mTOR inhibitor with efficacy in metastatic RCC (mRCC). We characterized the genomic profile of RCC tumors from metastatic sites and assessed w...
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| Τόπος έκδοσης: | Clin Genitourin Cancer |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6175670/ https://ncbi.nlm.nih.gov/pubmed/29754934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clgc.2018.04.001 |
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