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Quantitative single cell analysis uncovers the life/death decision in CD95 network

CD95/Fas/APO-1 is a member of the death receptor family that triggers apoptotic and anti-apoptotic responses in particular, NF-κB. These responses are characterized by a strong heterogeneity within a population of cells. To determine how the cell decides between life and death we developed a computa...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Buchbinder, Jörn H., Pischel, Dennis, Sundmacher, Kai, Flassig, Robert J., Lavrik, Inna N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175528/
https://ncbi.nlm.nih.gov/pubmed/30256782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006368
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