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Evaluation of Eluxadoline Effect on Cardiac Repolarization

This study evaluated the effects of eluxadoline, a mixed μ‐opioid receptor (OR) and κ‐OR agonist and δ‐OR antagonist, on cardiac repolarization. This evaluator‐blinded, placebo‐ and positive‐controlled, 4‐period crossover study randomized healthy men and women to single oral doses of eluxadoline (th...

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Bibliografische gegevens
Gepubliceerd in:Clin Pharmacol Drug Dev
Hoofdauteurs: Bonifacio, Laura, Hunt, Thomas L., McIntyre, Gail, Dove, Leonard S., Covington, Paul S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175186/
https://ncbi.nlm.nih.gov/pubmed/29659201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.453
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