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Evaluation of Eluxadoline Effect on Cardiac Repolarization

This study evaluated the effects of eluxadoline, a mixed μ‐opioid receptor (OR) and κ‐OR agonist and δ‐OR antagonist, on cardiac repolarization. This evaluator‐blinded, placebo‐ and positive‐controlled, 4‐period crossover study randomized healthy men and women to single oral doses of eluxadoline (th...

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Bibliografske podrobnosti
izdano v:Clin Pharmacol Drug Dev
Main Authors: Bonifacio, Laura, Hunt, Thomas L., McIntyre, Gail, Dove, Leonard S., Covington, Paul S.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175186/
https://ncbi.nlm.nih.gov/pubmed/29659201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.453
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